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Colon cancer study backs blood stool screening test (2/23/2012 12:44:32 AM) NEW YORK (Reuters Health) - Although colon cancer screening is recommended by many organizations, less clear is which method is best to detect tumors and precancerous lesions. A new study in the New England Journal of Medicine suggests that a relatively inexpensive and non-invasive test may be just as effective as a colonoscopy. Strengthening The Intestinal Barrier May Prevent Cancer In The Rest Of The Body (2/22/2012 12:04:14 PM) A leaky gut may be the root of some cancers forming in the rest of the body, a new study published online Feb. 21 in PLoS ONE by Thomas Jefferson University researchers suggests. It appears that the hormone receptor guanylyl cyclase C (GC-C) - a previously identified tumor suppressor that exists in the intestinal tract - plays a key role in strengthening the body's intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens. A team led by Scott Waldman, M.D., Ph.D... Possible New Target For Cancer Therapy - Energy Network Within Cells (2/22/2012 9:24:19 AM) Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the numbers of mitochondria in cells could shrink human lung cancers transplanted into mice, a team of Chicago researchers report in the journal FASEB. Within each cell, mitochondria are constantly splitting in two, a process called fission, and merging back into one, called fusion... Early Cancer Detection Via New Blood Test: Research In The Early Stages Of Clinical Trials (2/22/2012 9:24:19 AM) A simple blood test is being developed by researchers at Ben-Gurion University of the Negev (BGU) and Soroka University Medical Center in Beer-Sheva, Israel that may provide early detection of many types of cancer. Prof. Kapelushnik of BGU's Faculty of Health Sciences and his team developed a device that illuminates cancer cells with less than a teaspoon of blood. The test uses infrared light to detect miniscule changes in the blood of a person who has a cancerous growth somewhere, even before the disease has spread... Prostate Cancer Progression Driven By Telomere Failure, Telomerase Activation (2/22/2012 9:24:19 AM) Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, researchers report in an Online Now article at the journal Cell. In a strain of mice engineered to develop prostate cancer, all mice that went through this two-step process developed lethal cancer and 25 percent had the disease spread to the spine. Two groups of mice that avoided this cycle developed only precancerous lesions or localized prostate cancer... Cancer Cells Destroyed By Blocking Telomerase But Resistance, Progression Provoked (2/22/2012 9:24:19 AM) Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive and spread, scientists report in Cell. "Telomerase is overexpressed in many advanced cancers, but assessing its potential as a therapeutic target requires us to understand what it does and how it does it," said senior author Ronald DePinho, M.D., president of The University of Texas MD Anderson Cancer Center... Potential For Development Of Tailor-Made Anticancer Agents Following Mapping Of Protein Inhibitors (2/22/2012 9:24:19 AM) A team of researchers at Karolinska Institutet has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs. The study is presented in the journal Nature Biotechnology, and will hopefully contribute to new cancer therapies with fewer detrimental side effects. PARP1 is a protein with enzymatic activity that governs repair of DNA damage in our cells... Reformulated Imatinib Eliminates Morphine Tolerance In Lab Studies (2/22/2012 9:24:19 AM) By reformulating the common cancer drug imatinib (Gleevec®), researchers have eliminated morphine tolerance in rats - an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center. Narcotics such as morphine are a mainstay of chronic pain treatment. Over time, tolerance to the pain-relieving effects of these drugs can develop, requiring increasing doses to control pain. In some cases, narcotics become ineffective... Birthday boy Mugabe says he has 'beaten Jesus Christ' (2/22/2012 6:47:54 AM) One-Minute Read Tue 21 Feb, AT 15:41 Africa Zimbabwean leader, 88, vows to stand in presidential elections, despite cancer rumours Egyptian firm in fake Avastin scam proves elusive (2/22/2012 4:05:03 AM) CAIRO (Reuters) - The trail of counterfeit copies of the multibillion-dollar cancer drug Avastin leads to an address in a crowded Cairo suburb, with no sign of the firm named by international suppliers as the source of the product. Venezuela's Chavez faces surgery (2/22/2012 2:04:33 AM) Venezuelan President Hugo Chavez, who had cancer last year, says he will have to undergo another operation to remove a small lesion. Janice Voss: American astronaut (2/22/2012 1:06:14 AM) The Nasa astronaut Janice Voss, who first worked for the US space agency as a teenager and flew five shuttle missions in seven years, died of breast cancer on 6 February at the age of 55. Voss flew four missions in the 1990s before a flight to the International Space Station in 2000. Nasa said that she was one of six women to fly in space at least five times.Related StoriesLord Carr of Hadley: Highly regarded Conservative minister whose Industrial Relations Act provoked bitter controversySarah Cullen: Reporter for ITN and 'Today' who found the authentic voices of the streetsMichael Davis: Bassist with the influential and incendiary MC5Johannes Heesters: Actor dogged by his Nazi associations Drug Combo Kills Pancreatic Cancer Cells (2/21/2012 9:25:08 PM) Combining gemcitabine with MRK003, an experimental drug, triggers a chain of events leading to pancreatic cancer cell death, researchers from Cambridge reported in the Journal of Experimental Medicine. The researchers explained that when the two drugs are combined, the effect of each one is multiplied, thus intensifying the destruction of pancreatic cancer cells... FDA acts to stem shortages of two cancer drugs (2/21/2012 5:04:33 PM) (Reuters) - The Food and Drug Administration plans to address a potentially life-threatening shortage of two leading cancer drugs by allowing one of them to be imported from abroad and rushing approval for a new manufacturer to make the second. Women May Be At Increased Cancer Risk Following Vitamin B And Omega-3 Supplementation (2/21/2012 10:24:14 AM) Women with a previous history of cardiovascular pathologies seem to have a higher cancer risk after five years of Vitamin B and omega-3 supplementation. The research is published in detail in the Archives of Internal Medicine. Although some studies have suggested that supplementation with B vitamins has some benefits for protecting against cancer, the few randomised clinical trials conducted internationally in recent years remain equivocal. The results of studies of the influence of supplementation with polyunsaturated fatty acids have been mixed... A Promising Novel Therapeutic Target In Cancer - The USP15 Biological Thermostat (2/21/2012 10:24:14 AM) After years studying the molecular bases of glioblastoma - the most common brain tumor and one of the most aggressive of all cancers, the group led by Dr. Joan Seoane , Director of Translational Research at the Vall d'Hebron Institute of Oncology (VHIO) and ICREA Research Professor has published a study in Nature Medicine identifying USP15 as a critical protein in cancer which, thanks to its molecular characteristics, shows enormous therapeutic promise. USP15 promotes tumor progression by activating the TGFβ pathway... Cancer Evolution Discussed At Prestigious Conference (2/21/2012 10:24:14 AM) Professor Mike Stratton, Director of the Wellcome Trust Sanger Institute, talked about 'the evolution of the cancer genome' at the prestigious 2012 American Association for the Advancement of Science annual meeting. The AAAS annual meeting is one of the world's most widely recognized science events. In 2000, Mike started the Cancer Genome Project at the Wellcome Trust Sanger Institute, which conducts high-throughput, systematic genome-wide searches for genetic mutations in human cancer... New Approach To Fighting Cancer - New Combo Of Chemo And Malaria Drug Delivers Double Punch To Tumors (2/21/2012 9:24:24 AM) Blocking autophagy - the process of "self-eating" within cells -- is turning out to be a viable way to enhance the effectiveness of a wide variety of cancer treatments. Specifically, blocking the action of an acidic inner cell part, which acts like a stomach and chews up proteins for recycling, is the main attack strategy, says Ravi K. Amaravadi, MD, an assistant professor of Medicine at the Perelman School of Medicine and Abramson Cancer Center at the University of Pennsylvania... Smokeless Tobacco Substitutes Save Lives (2/21/2012 9:24:24 AM) Substituting smokeless tobacco products can save smokers' lives, and there is a scientific foundation that proves it. That is the message Brad Rodu, D.D.S., professor of medicine at the University of Louisville (UofL) School of Medicine and the Endowed Chair in Tobacco Harm Reduction at UofL's James Graham Brown Cancer Center, delivered at the Annual Meeting of the American Association for the Advancement of Science. Rodu spoke at the session, "Harm Reduction: Policy Change to Reduce the Global Toll of Smoking-Related Disease... 'Promising' pancreas cancer drug (2/21/2012 8:04:15 AM) Scientists report promising results for an experimental pancreatic cancer drug treatment. Prostate drug is approved for use (2/21/2012 7:44:59 AM) A drug that can extend the life of men with advanced prostate cancer by more than three months is approved for use in Wales. Anne Nolan: "I felt nothing when my father died. But telling the truth about him changed everything" (2/21/2012 1:45:19 AM) The Nolans, Ireland's most famous singing siblings, have lived through it all – fallouts, marriage break-ups, musical mockery and no fewer than three cancer diagnoses – all in the glare of the media. But in the 33 years since their most successful song, "I'm in the Mood for Dancing", nothing was quite so shocking as the news that Anne, the eldest daughter of the eight siblings, was sexually abused by their father – and that, when she was just 16, he even suggested they run away together and live as man and wife.Related StoriesThe sci-fi movie Hollywood would not dare to makeMcQueen reigns again on London catwalk as label returns home in styleSay no to the scalpelThe 10 Best pre-school toysSimon Annand: Behind closed doors Health Behaviors Worse Among Female Cancer Survivors (2/20/2012 10:24:37 PM) Women who survive cancer receiving mammography screening have "worse health behaviors", than those who had never had cancer and receiving mammography screening, according to a study by researchers at Moffitt Cancer Center in Tampa, Fla., and the Mayo Clinic in Rochester, Minn. The study was published in the American Journal of Clinical Oncology. The team questioned 2,713 female cancer survivors aged 35+ receiving mammography screening, and compared their responses of 19,947 women with no previous breast cancer presenting for mammography screening... Less Addictive Cigarettes Preferred By Smokers (2/20/2012 10:24:37 PM) Results from an International Tobacco Control (ITC) United States Supplemental Survey, published recently in the journal BMC Public Health , reveal that smokers strongly favor decreasing the addictiveness of cigarettes. Lead investigator Andrew Hyland, PhD, Chair of the Department of Health Behavior at the Roswell Park Cancer Institute (RPCI), and his team, surveyed 678 smokers between November 2009 and January 2010 on their attitudes and beliefs about the Family Smoking Prevention and Tobacco Control Act (FSPTCA). In 2009, the Act was signed into law, authorizing the U.S... Turnout steady at Komen race despite controversy (2/20/2012 8:30:32 PM) El PASO, Texas (Reuters) - The decision by Susan G. Komen for the Cure to cut, and later restore, funding for Planned Parenthood did not seem to affect turnout on Sunday for the first Race for the Cure breast cancer fundraiser held since the controversy erupted this month. Florence and Pulp confirmed for Teenage Cancer Trust benefit (2/20/2012 11:49:38 AM) The line-up for this year's Teenage Cancer Trust concerts has been announced and people will be able to choose between 1990s indie rock, current chart toppers and stand-up comedy Florence heads Cancer Trust gigs (2/20/2012 11:44:40 AM) Example and Pulp will also play shows at London's Royal Albert Hall in aid of the Teenage Cancer Trust. Expert Says Four New Drugs Will Change Prostate Cancer Care (2/20/2012 11:44:40 AM) After a decade and a half of near stagnation, four new drugs could help make advanced prostate cancer a chronic illness instead of a terminal disease, a leading Colorado prostate cancer expert says. "It's not just chemotherapy. The drugs have different and innovative methods of action. One is a bone protective agent; another's a more effective hormone agent; another is radiotherapy; and the final one is the first drug tested for cancer immunotherapy," says E... Targeted Tumor Freezing Therapy Increases Ovarian Cancer Survival (2/20/2012 11:44:40 AM) Ovarian cancer, which killed 15,000 American women last year, is one of the deadliest forms of cancer. A team of Wayne State University School of Medicine researchers recently proved that freezing tumors increases survival rates in ovarian cancer patients. The "freeze and destroy" technique is an alternative for local treatment of cancerous tumors, said Peter Littrup, M.D., professor of radiology in the School of Medicine and director of imaging core and radiological research at the Barbara Ann Karmanos Cancer Institute... Cancer drug funding set for review amid postcode-lottery approvals concerns (2/20/2012 9:28:26 AM) THE way patients apply for funding for new cancer drugs and other medicines in Wales is to be reviewed. Researchers Test Nanoscale Carbon Clusters For Chemotherapy (2/20/2012 9:24:20 AM) A mixture of current drugs and carbon nanoparticles shows potential to enhance treatment for head-and-neck cancers, especially when combined with radiation therapy, according to new research by Rice University and the University of Texas MD Anderson Cancer Center. The work blazes a path for further research into therapy customized to the needs of individual patients. The therapy uses carbon nanoparticles to encapsulate chemotherapeutic drugs and sequester them until they are delivered to the cancer cells they are meant to kill... Study Details On-off Switch That Promotes Or Suppresses Breast Cancer (2/20/2012 9:24:20 AM) Signals can tell cells to act cancerous, surviving, growing and reproducing out of control. And signals can also tell cells with cancerous characteristics to stop growing or to die. In breast cancer, one tricky signal called TGF-beta does both - sometimes promoting tumors and sometimes suppressing them. A University of Colorado Cancer Center study recently published in the journal Oncogene details how tumors may flip the TGF-beta signalling switch, allowing doctors to delete the pathway entirely when it promotes tumors, and leave it intact when it's still working to suppress them... New Guiding Principles For Cancer Genomics: Understanding Chromosome Reshuffling, Looking To The Genome's 3D Structure (2/20/2012 9:24:20 AM) That our chromosomes can break and reshuffle pieces of themselves is nothing new; scientists have recognized this for decades, especially in cancer cells. The rules for where chromosomes are likely to break and how the broken pieces come together are only just now starting to come into view... Virus' Coats Used In Nano-Technology To Fool Cancer Cells (2/20/2012 9:24:20 AM) While there have been major advances in the detection, diagnosis, and treatment of tumors within the brain, brain cancer continues to have a very low survival rate in part to high levels of resistance to treatment. New research published in BioMed Central's open access Journal of Nanobiotechnology has used Sendai virus to transport Quantum Dots (Qdots) into brain cancer cells and to specifically bind Qdots to epidermal growth factor receptor (EGFR) which is often over-expressed and up-regulated in tumors... Potential Treatment Target Identified For KRAS-Mutated Colon Cancer (2/20/2012 9:24:20 AM) Researchers from the Massachusetts General Hospital (MGH) Cancer Center have identified a new potential strategy for treating colon tumors driven by mutations in the KRAS gene, which usually resist both conventional and targeted treatments. In a paper appearing in Cell, the team reports that targeting a later step in the pathway leading from KRAS activation to tumor growth may be able to halt the process. "Not all KRAS-mutant colon cancers are the same," says Daniel Haber, MD, PhD, director of the MGH Cancer Center and co-corresponding author of the Cell report... New Paths To Treat Cancer, Other Diseases, With The Help Of Video Games (2/20/2012 9:24:20 AM) The cure for cancer comes down to this: video games. In a research lab at Wake Forest University, biophysicist and computer scientist Samuel Cho uses graphics processing units (GPUs), the technology that makes videogame images so realistic, to simulate the inner workings of human cells. "If it wasn't for gamers who kept buying these GPUs, the prices wouldn't have dropped, and we couldn't have used them for science," Cho says. Now he can see exactly how the cells live, divide and die. And that, Cho says, opens up possibilities for new targets for tumor-killing drugs... New Hope For Blood Disorders Provided By Cell Signaling Discovery (2/20/2012 9:24:20 AM) Walter and Eliza Hall Institute scientists have revealed new details about how cell signalling is controlled in the immune system, identifying in the process potential new therapeutic targets for treating severe blood disorders. Dr Jeff Babon and Professor Nick Nicola, from the institute's Structural Biology and Cancer and Haematology divisions respectively, study interactions between internal cell signalling proteins called JAKs (Janus kinases) and SOCS (Suppressors of Cytokine Signalling). Dr Babon said the proteins were essential for blood system maintenance and immune responses... Major Breakthrough In Nanosurgery And The Fight Against Cancer (2/20/2012 9:24:20 AM) Researchers at Polytechnique Montreal have succeeded in changing the genetic material of cancer cells using a brand-new transfection method. This major breakthrough in nanosurgery opens the door to new medical applications, among others for the treatment of cancers. A light scalpel to treat cancerous cells The unique method developed by Professor Michel Meunier and his team uses a femtosecond laser (a laser with ultra-short pulses) along with gold nanoparticles... Turnout steady at Komen charity race despite controversy (2/20/2012 3:04:02 AM) El PASO, Texas (Reuters) - The decision by Susan G. Komen for the Cure to cut, and later restore, funding for Planned Parenthood did not seem to affect turnout on Sunday for the first Race for the Cure breast cancer fundraiser held since the controversy erupted this month. "DNA Origami" Robots Target Cancer Cells (2/19/2012 11:05:14 PM) Using a technique called "DNA origami", US scientists have made programmable molecule-transporting nanorobots that can seek out particular cell targets and deliver specific instructions for them to follow. One example of such use could be to tell cancer cells to destroy themselves. The researchers write about their findings in Friday's online issue of Science... Black Sabbath axe shows as Iommi continues cancer battle (2/19/2012 8:24:28 PM) The reunited members of BLACK SABBATH have cancelled a number of upcoming shows as guitarist TONY IOMMI continues his cancer battle. Thousands of patients may have been misdiagnosed at a hospital in Bristol (2/19/2012 2:12:58 PM) Cases include retired nurse Catherine Calland, pictured, who has terminal cancer but was dismissed by doctors as 'hysterical' for wanting a breast lump removed. Prostate cancer patients in Wales to get breakthrough drug (2/19/2012 12:08:53 PM) MEN with advanced prostate cancer will get access to a new breakthrough treatment in Wales. Novel Technology Could Potentially Seek Out Cancer Cells And Cause Them To Self-Destruct (2/19/2012 10:44:15 AM) Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a robotic device made from DNA that could potentially seek out specific cell targets within a complex mixture of cell types and deliver important molecular instructions, such as telling cancer cells to self-destruct. Inspired by the mechanics of the body's own immune system, the technology might one day be used to program immune responses to treat various diseases. The research findings appear in Science... Protein That Functions In Normal Breast May Also Contribute To Breast Cancer Metastasis (2/18/2012 9:24:26 AM) The trefoil factor 3 (TFF3) protein protects and maintains the integrity of the epithelial surface in the normal breast. New research has found that while TFF3 protein expression is higher in well-differentiated low grade tumors and therefore associated with features of a good prognosis, it has a more sinister role in breast cancer invasion and metastasis. The report is published in the March issue of the American Journal of Pathology. "Our findings suggest that TFF3 is regulated by estrogen and has beneficial properties in breast epithelia," says lead investigator Felicity E.B... New Drug Target For Lung Cancer Discovered By Salk Researchers (2/18/2012 9:24:26 AM) Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies. The scientists discovered that blocking the activity of the enzyme IKK2, which helps activate the body's inflammation response, slowed the growth of tumors in mice with lung cancer and increased their lifespan. The findings, reported in Nature Cell Biology, suggest that drugs that hinder the ability of the enzyme to command cellular activity might prove effective as lung cancer therapies... Fooling Cancer Cells With Nano-Technology (2/17/2012 10:04:12 PM) Survival rates of brain cancer continue to remain low, despite the substantial advances in detection, diagnosis, and treating tumors within the brian. This low survival rate is partly due to high levels of resistance to treatment. According to a study published in BioMed Central's open access Journal of Nanobiotechnology, researchers from the City College of New York have used Sendai virus to carry Quantum Dots (Qdots) into brain cancer cells and to specifically attach Qdots to epidermal growth factor receptor (EGFR), which is frequently up-regulated and over-expressed in tumors... Botanical Formula Effective In Treating Prostate Cancer (2/17/2012 10:04:12 PM) A study published online in The International Journal of Oncology reports findings from a team of scientists at Indiana University, Methodist Research Institute, who examined a botanical formula containing botanical extracts, phytonutrients, botanically-enhanced medicinal mushrooms, and antioxidants, that kills aggressive prostate cancer tumors. The researchers conducted experiments in mice using a human prostate cancer tumor model... Computerized System Matches Patient To Clinical Trial More Efficiently (2/17/2012 10:04:12 PM) The Moffit Cancer Center has received a new patent for a computerized system that efficiently matches the right patient with the right clinical trial. The newly patented system's database contains thousands of patient-donated biological tissue or tumor samples, and can rapidly match a registered patient's personal molecular profile to the molecular design of the drug that aims to target their disease at the molecular level. The system can potentially speed up clinical trials and assist in reducing the time for gaining market approval for critically needed new drugs... Repeat Prostate Biopsies - PROGENSA® PCA3 Assay Helps Determine, Approved By FDA (2/17/2012 10:04:12 PM) On Wednesday, the US Food and Drug Administration (FDA) approved Gen-Probe's PROGENSA® PCA3 (Prostate Cancer gene 3) assay, the first molecular test to help determine whether men with a previous negative biopsy need a repeat biopsy. Carl Hull, Gen-Probe's Chairman and Chief Executive Officer said: "When used in conjunction with other diagnostic information, our PROGENSA PCA3 assay provides clinically important information that helps physicians and their patients make better, more informed decisions about one of the most vexing problems in prostate cancer diagnosis... Blood Cancer Patients To Benefit From Stem Cell Research Breakthrough (2/17/2012 10:04:12 PM) A landmark study published Online First in The Lancet Oncology , describes the discovery of a unique matching mechanism that affects the outcome of blood stem cell transplants and helps improving survival rates for sufferers from leukemia and other blood cancers. Often, the last glimmer of hope for blood cancer sufferers who remain unresponsive to all other treatment options is to receive blood stem cells, also called haemopoietic cells, from an unrelated, living donor. An allele is an alternative form of a gene, i.e... Men opting for costly new prostate cancer treatment, study shows (2/17/2012 9:24:04 PM) NEW YORK (Reuters Health) - Men diagnosed with localized prostate cancer are more likely to be treated with proton beam therapy, a novel form of radiation therapy, if the technology is available nearby, a new study found. Denmark's CareMed says shipped fake Avastin unwittingly (2/17/2012 9:24:04 PM) LONDON/COPENHAGEN (Reuters) - Danish drug distributor CareMed said it was an unwitting link in the journey of fake cancer medicine Avastin from Switzerland to Britain, in the latest twist in a saga that began when the counterfeit drugs surfaced in the United States last year. 'DNA robot' targets cancer cells (2/17/2012 3:24:16 PM) Researchers show off a "robot" made of DNA molecules that can target cancer cells and release a payload of antibodies once they find them. How Zygotes Sort Out Imprinted Genes (2/17/2012 11:44:04 AM) Writing in the February 17, 2012 issue of the journal Cell, researchers at the Ludwig Institute for Cancer Research, the University of California, San Diego School of Medicine and the Toronto Western Research Institute peel away some of the enduring mystery of how zygotes or fertilized eggs determine which copies of parental genes will be used or ignored. In developing humans and other mammals, not all genes are created equal - or equally used. The expression of certain genes, known as imprinted genes, is determined by just one copy of the parents' genetic contribution... Black opens up about secret cancer battle (2/17/2012 11:24:09 AM) Veteran actress KAREN BLACK has opened up about the 2011 cancer battle she kept from fans. New Method Makes It Easier To Treat Prostate And Pancreatic Cancer (2/17/2012 10:25:08 AM) Laser light in combination with certain drugs - known as photodynamic therapy - can destroy cancer tumours, but is today used mostly to cure skin cancer. The reason that internal tumours are not treated with the method is that the technology does not exist to check that the precise amount of light is administered. However, software developed by researchers in atomic physics at Lund University in Sweden looks like being able to solve the problem... Study Finds Female Cancer Survivors Have Worse Health Behaviors Than Women With No Cancer History (2/17/2012 10:25:08 AM) A recent study conducted by researchers at Moffitt Cancer Center in Tampa, Fla., and the Mayo Clinic in Rochester, Minn., has found that female cancer survivors receiving screening mammography have "worse health behaviors" than women receiving mammography screening and who had never had cancer. The study was published in a recent issue of the American Journal of Clinical Oncology... Helping Patients Tackle Geographic Challenges To Access Clinical Trials (2/17/2012 10:25:08 AM) As oncologists already know and newly diagnosed lung cancer patients learn, the kind of treatment given to patients is increasingly becoming dependent on the specific gene mutation present in the cancer. But, as lung cancer moves from being one common disease to multiple different diseases at the molecular level, learning about and getting access to the right treatment within clinical trials can be challenging for these subpopulations of patients that may be widely dispersed around the globe. Dr... Survival In Medulloblastoma Model Extended By Oncolytic Virus (2/17/2012 10:25:08 AM) A strain of measles virus engineered to kill cancer cells prolongs survival in a model of medulloblastoma that is disseminated in the fluid around the brain, according to a new study by researchers at Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute and the Mayo Clinic. Treatment with the oncolytic virus called MV-GFP extended survival of animals with disseminated human medulloblastoma up to 122 percent, with treated animals surviving 82 days on average versus 37 days for controls... Therapeutic Cancer Vaccines Show Promise (2/17/2012 10:25:08 AM) Therapeutic cancer vaccines, which stimulate the body's immune system to target and destroy cancer cells, are being used in combination with conventional chemotherapy with growing success, as described in several illuminating articles in Cancer Biotherapy and Radiopharmaceuticals, a peer-reviewed journal from Mary Ann Liebert, Inc. These articles are available free online.(1) The U.S. FDA recently approved the first cancer therapeutic vaccine for treatment of metastatic prostate cancer... In Malnourished Cancer Patients, Oral Nutritional Interventions Improve Nutritional Intake And QOL (2/17/2012 10:25:08 AM) Oral nutritional interventions help increase nutritional intake and improve some aspects of quality of life (QOL) in malnourished cancer patients or those who are at nutritional risk, but do not effect mortality, according to a study published in the Journal of the National Cancer Institute. The American Cancer Society estimated 12 million new cancer diagnoses worldwide in 2007, expecting this to more than double in the next 50 years... Researchers Identify Cycle Of Platelet Production In Ovarian Cancer Patients (2/17/2012 10:25:08 AM) Highly elevated platelet levels fuel tumor growth and reduce the survival of ovarian cancer patients, an international team of researchers led by scientists at The University of Texas MD Anderson Cancer center reports in the New England Journal of Medicine. By pinpointing a powerful cause-and-effect relationship at the heart of a clinical observation that dates back more than 100 years, the team's findings reveal a new factor in cancer progression and new potential approaches for treatment... Would Cancer Treatment Be Enhanced By Low Molecular Weight Heparin? (2/17/2012 9:24:04 AM) For decades, the blood thinner heparin has been used to prevent and treat blood clots. Could it be just as effective in treating cancer? In an editorial published in the New England Journal of Medicine, researchers from McMaster University and the University at Buffalo suggest conclusive answers to key questions on the benefits of low molecular weight heparin (LMWH) for cancer patients remain elusive - despite promising results from large studies. Co-authors of the editorial are Dr... Ovarian Cancer - Best Imaging Technique Revealed (2/17/2012 1:25:43 AM) According to a study published in the journal Radiology, researchers from Cancer Research UK's Cambridge Experimental Cancer Medicine Center at the University of Cambridge, have determined that the best method to monitor how women with late-stage ovarian cancer are responding to treatment may be a magnetic resonance imaging (MRI) technique. The technique measures the movement of water molecules within the tumor... Tasmanian devil at risk of extinction from contagious cancer spread by biting (2/17/2012 1:05:24 AM) Researchers have sequenced the genome of a contagious cancer that is threatening the Tasmanian devil with extinction. The cancer is spread by biting and came from one 'devil' 15 years ago. Astra takes brand cancer drug straight to patients (2/17/2012 12:23:52 AM) (Reuters) - AstraZeneca Plc is selling breast cancer drug Arimidex directly to U.S. patients, offering an option for people who want to pay for the brand instead of generic versions. How Much Do Nutritional Interventions Help Malnourished Cancer Patients? (2/17/2012 12:05:12 AM) A study published February 15 in the Journal of the National Cancer Institute, reveals that oral nutritional interventions help malnourished cancer patients and individuals at nutritional risk improve some aspects of quality of life (QOL), as well as increase nutritional intake. However, the researchers found that these interventions did not affect mortality. In 2007, The American Cancer Society estimated that 12 million individuals worldwide would develop cancer, and they estimate this figure to more than double in the next five decades... Cancer centre to open at hospital (2/16/2012 6:04:05 PM) A cancer support network has been awarded a £3m grant to open a new centre at the Forth Valley Royal Hospital. Researchers Reveal Digital Transcriptome Of Breast Cancer (2/16/2012 5:45:18 PM) GW Cancer Research Team in the Department of Biochemistry and Molecular Biology, in the School of Medicine and Health Sciences, published a study that is the first of its kind to use mRNA sequencing to look at the expression of genome, at a unprecedented resolution at the current time, in three types of breast cancer. The study titled, "Transcriptomic landscape of breast cancer through mRNA sequencing," is published in the Feb. 14 edition of the journal, Scientific Reports, a new open access Nature journal for large volume data... B Vitamin Plus Omega-3 Supplements Do Not Protect Cardiovascular Disease Survivors From Cancer (2/16/2012 5:45:18 PM) A study published Online First by Archives of Internal Medicine, one of the JAMA/Archives journals, reveals that for individuals with previous cardiovascular disease, taking vitamin B and omega-3 fatty acid supplements for cancer prevention does not seem to beneficial. The study is part of the journal's Less is More series. Although it is believed that proper nutrition helps prevent cancer, researcher still do not fully know about the roles of individual nutrients in different populations... Skydive in aid of cancer charity (2/16/2012 1:08:14 PM) DAREDEVILS are invited to join in a charity parachute day in support of cancer care. Anti-Angiogenic Drugs May Be Effective Against New Subtype Of Ovarian Cancer (2/16/2012 11:04:16 AM) Scientists at Dana-Farber Cancer Institute have identified a subtype of ovarian cancer able to build its own blood vessels, suggesting that such tumors might be especially susceptible to "anti-angiogenic" drugs that block blood vessel formation. In a study published in the online journal PloS ONE, the investigators estimate that the subtype may account for a third of all serous ovarian cancers, a common cancer of the surface of the ovaries... Molecule Is Important Step Towards Creating Drugs That Can Go After Rogue DNA Directly (2/16/2012 11:04:16 AM) Chemists at The University of Texas at Austin have created a molecule that's so good at tangling itself inside the double helix of a DNA sequence that it can stay there for up to 16 days before the DNA liberates itself, much longer than any other molecule reported. It's an important step along the path to someday creating drugs that can go after rogue DNA directly. Such drugs would be revolutionary in the treatment of genetic diseases, cancer or retroviruses such as HIV, which incorporate viral DNA directly into the body's DNA... Biosensors Inspired By Nature (2/16/2012 11:04:16 AM) Over their 3.8 billion years of evolution, living organisms have developed countless strategies for monitoring their surroundings. Chemists at UC Santa Barbara and University of Rome Tor Vergata have adapted some of these strategies to improve the performance of DNA detectors. Their findings may aid efforts to build better medical diagnostics, such as improved HIV or cancer tests. Their research is described in an article published this week in the Journal of the American Chemical Society. Nature often serves as a source of inspiration for the development of new technologies... Breast Cancer Cells Transformed Into Cancer Stem Cells By Radiation Treatment (2/16/2012 10:04:08 AM) Breast cancer stem cells are thought to be the sole source of tumor recurrence and are known to be resistant to radiation therapy and don't respond well to chemotherapy. Now, researchers with the UCLA Department of Radiation Oncology at UCLA's Jonsson Comprehensive Cancer Center report for the first time that radiation treatment - despite killing half of all tumor cells during every treatment - transforms other cancer cells into treatment-resistant breast cancer stem cells. The generation of these breast cancer stem cells counteracts the otherwise highly efficient radiation treatment... Pre-Clinical Study Shows Delay In Tumor Growth And Prolonged Survival Time When Chemotherapy Combined With Immunotherapy (2/16/2012 10:04:08 AM) An international team of scientists in Japan, Switzerland, and the United States has confirmed that combining chemotherapy and immunotherapy in cancer treatment enhances the immune system's ability to find and eliminate cancer cells, even when the cancer-associated proteins targeted by the immune system are hidden behind the cancer cell membrane. In a study published in Cancer Research by Noguchi et al... Stars of Strictly Come Dancing tour sign up to help Vanessa Riddle appeal (2/16/2012 8:48:22 AM) EXCLUSIVE: Stars on the Strictly Come Dancing tour have joined the campaign to help Scots cancer sufferer Vanessa Riddle. Doctors scour drug supplies after fake Avastin found (2/16/2012 8:25:08 AM) NEW YORK (Reuters) - A U.S. distributor of phony vials of the widely-used cancer drug Avastin aroused suspicion at doctor's offices as early as July, well before health regulators issued their own warning and sparked new alarm over counterfeit medicines. Prostate cancer care 'a disgrace', says experts' report (2/16/2012 7:48:27 AM) Health experts said research funding for the disease is a fifth of the amount dedicated to fighting breast cancer – despite being just as deadly Bureaucracy May Be Putting Lives At Risk, Europe (2/16/2012 2:04:17 AM) A European Parliament event to discuss how EU legislation has negatively affected the treatment received by children and adolescents has marked International Childhood Cancer Day - 15th February. The meeting was hosted in association with the European Society for Paediatric Oncology (SIOPE) to raise awareness of the many hurdles faced by patients and those who care for them as a result of the EU Clinical Trials Directive (CTD)... Heparin - Possible Cancer Treatment (2/16/2012 2:04:17 AM) Although the blood thinner heparin has been used for several decades to prevent and treat blood clots, researchers are now questioning whether the drug could be effective in treating cancer. Even though results from large studies have been promising, a study by investigators from McMaster University and the University at Buffalo, suggests that these studies still fail to provide precise answers to key questions, with regard to the benefits of low molecular weight heparin (LMWH) for cancer patients. The study is published today in the New England Journal of Medicine... Fake Avastin (Bevacizumab) Found In USA (2/16/2012 2:04:17 AM) Fake cancer drug, Avastin (bevacizumab) has been distributed in the USA, according to statement issued by Roche, Genentech and the FDA (Food and Drug Administration) today. Roche warns that the counterfeit medication does not have the active ingredient - bevacizumab - and should not be used or taken. Roche says it was told about the fake Avastin from a non-US health authorities. The company added that the bogus drug comes from another country, but gave no more details... Counterfeits of cancer drug Avastin found in U.S. (2/15/2012 8:24:32 PM) (Reuters) - Counterfeit versions of Roche's multi-billion cancer drug Avastin have been distributed in the United States, the Swiss drugmaker and its U.S. biotech unit Genentech said on Tuesday. Rare mutations tied to breast, pancreatic cancers: study (2/15/2012 8:24:32 PM) NEW YORK (Reuters Health) - Mutations in genes that fix mismatched DNA may put people at extra risk for breast cancer and pancreatic cancer, in addition to their well-known ties to colon and endometrial cancers, a new report suggests. DiagnoCure gets FDA nod for prostate cancer test, shares jump (2/15/2012 6:44:02 PM) (Reuters) - Canada's DiagnoCure Inc said it received U.S. regulatory approval for a prostate cancer test that may help avoid unnecessary biopsies, sending its shares to their highest in about 18 months. In prostate cancer, other death risks may be higher (2/15/2012 6:44:02 PM) NEW YORK (Reuters Health) - Some men with prostate cancer may have increased risks of dying from causes other than the cancer itself, a new study finds. Targeting Leukemia Stem Cells (2/15/2012 5:24:06 PM) New research takes aim at stubborn cancer stem cells that are thought to be responsible for treatment resistance and relapse. The study, published by Cell Press in the February 14 issue of the journal Cancer Cell, provides insight into mechanisms associated with the survival of leukemia stem cells and identifies a potential therapeutic target that is specific for these dangerously persistent cells. Chronic myelogenous leukemia (CML) is a cancer of the white blood cells for which tyrosine kinase inhibitors are currently the first line of therapy... "A life well lived": Royal reporter James Whitaker's life in pictures (2/15/2012 2:06:59 PM) Tribute to the former Daily Mirror royal editor, who lost his battle with cancer this morning aged 71 News: Coleg Llandrillo Cymru column Education Matters - Promoting wellbeing in the community (2/15/2012 1:47:52 PM) BREAST cancer is now the most common cancer in the UK, where almost 50,000 women are diagnosed with breast cancer each year – that’s around 130 women every day. Although treatments and early detection rates are improving, there is a lack of resources in certain areas of the country to promote the day-to-day well-being of patients. Increase In Injectable Treatment For Blood Clots In Advanced Cancer Patients (2/15/2012 10:24:45 AM) The use of an injectable, clot-preventing drug known as Low Molecular Weight Heparin to treat patients with advanced cancer complicated by blood clots increased steadily between 2000 and 2007, according to a new study published in The Oncologist, funded by the National Cancer Institute and led by Kaiser Permanente Colorado. However, despite previous research indicating LMWH is the preferred first-line treatment for cancer patients experiencing blood clots, use of LMWH is low compared to another commonly used anticoagulant, warfarin... First Prospective Analysis Links Breast And Pancreatic Cancer Risk With Lynch Syndrome (2/15/2012 10:24:45 AM) A new prospective study of patients with Lynch syndrome - an inherited disorder of cancer susceptibility caused by mutations in specific DNA repair genes - provides the first strong evidence that people with Lynch syndrome face significantly increased risks of breast and pancreatic cancers. The study also provided new, clearer estimates of the risks of cancers already recognized to be associated with Lynch syndrome, including those of the colon, uterus, ovary, kidney, stomach and bladder... New Research Into Immune Tolerance Studies The Sensing Of Self And Non-Self (2/15/2012 10:24:45 AM) At the most basic level, the immune system must distinguish self from non-self, that is, it must discriminate between the molecular signatures of invading pathogens (non-self antigens) and cellular constituents that usually pose no risk to health (self-antigens). The system is far from foolproof. Cancer cells can undergo unchecked proliferation, producing self-antigens that are tolerated by the immune system, rather than being targeted for destruction. At the opposite extreme, a range of so-called autoimmune disorders can result when healthy cells in the body are misidentified as hazards... Increased Risk Of Testicular Cancer When Fetus Exposed To Radiation (2/15/2012 9:24:06 AM) Male fetuses of mothers that are exposed to radiation during early pregnancy may have an increased chance of developing testicular cancer, according to a study in mice at The University of Texas MD Anderson Cancer Center. The article was published today in PLoS ONE. The study is the first to find an environmental cause for testicular germ cell tumors, the most common cancer in young Caucasian men... Orgasms Often Unafffected Following Nerve Sparing In Prostate Cancer Surgery (2/15/2012 9:24:06 AM) The vast majority of men who have a prostate cancer operation can retain their ability to orgasm if the surgery is carried out without removing the nerves that surround the prostate gland like a hammock, according to a study in the February issue of the urology journal BJUI. American researchers from Cornell University, New York, studied 408 patients who received robot-assisted laparoscopic radical prostatectomy (RALP) from a single surgeon between January 2005 and June 2007. They focused on men who were able to achieve orgasm before surgery and the average follow-up was three years... Woman battling to get ovary back and become a mother after it was removed and frozen before cancer treatment (2/15/2012 9:04:13 AM) Kate Oliver, 28, pictured, from Yelverton, Devon was diagnosed with rare bone cancer Ewing’s sarcoma when she was 16. How a dose of aspirin can help to halt cancer (2/15/2012 8:44:49 AM)
THE humble painkiller aspirin could be the secret weapon to beat cancer after scientists discovered it can stop tumours spreading. North Wales News: Tributes to North Wales woman who died after suffering cancer eight times (2/15/2012 8:08:34 AM) HEARTFELT tributes have been paid to an inspirational woman struck down with a rare form of cancer eight times. Gene alert for breast and ovarian cancer (2/15/2012 8:08:33 AM) Women with mutations in the BRCA1 gene have a much higher chance of developing breast cancer and ovarian cancer, the study pointed out Breast cancer sufferers should be tested for genetic fault, study urges (2/15/2012 2:44:46 AM) Women with mutations in the BRCA1 gene have a much higher chance of developing breast cancer but also a higher risk of ovarian cancer. |
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